Our Vision: The Bernstein lab pursues a systems-level, molecular understanding of chromatin structure and the epigenetic regulation of cellular state, and how these control systems go awry in diseases like cancer.
Our Approach: We develop technologies to profile and perturb the epigenome. We work closely with clinicians at MGH and our parter hospitals to apply these technologies to cancer cell models and primary tumors. We also pursue large scale profiling efforts in our dedicated facility at the Broad Institute.
Our Funding: Our research is supported by an NCI Pioneer Award, NHGRI ENCODE, NHGRI Technology Development, The Ludwig Center at Harvard, Liposarcoma Genome Project, ACCRF, and the Kayden family.