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We are combining tools in cell biology, biochemistry and molecular biology with next-generation sequencing to achieve increasingly precise, genome-wide views of chromatin.

Cancer Epigenetics

Applying epigenomic technologies to characterize the transcriptional and epigenetic landscapes of cancer stem cells.

Stem Cell Epigenetics

Current studies are leveraging a new generation of experimental assays to characterize the functions of bivalent domains and to understand the mechanisms that underlie their establishment and function.